23andMe will sequence your entire genome
30x whole genome sequencing is here!
You asked. We heard. We are excited to announce the launch of our 30x whole genome sequencing service today. It's available in 188 countries at an unmatched price of $ 299.
The most comprehensive genetic test
30-fold whole genome sequencing is the gold standard for genetic testing. While most other commercially available DNA tests (e.g. 23andMe and AncestryDNA) read your DNA at around 600,000 positions (~ 0.02%), Whole Genome Sequencing reads over 6,000,000,000 positions in your genome (~ 100% ). With 30x coverage, whole genome sequencing is also much more accurate, as each letter of DNA is read an average of 30 times. This generates a thousand times more information, which is also more accurate, and enables more comprehensive reporting on traits and ancestry. However, until now it has been inaccessible to most people due to the cost of sequencing the entire genome. By offering a 30-fold sequencing of the entire genome for $ 299, we were able to more than double the price.
The most advanced reporting
We bundle our 30-fold whole genome sequencing with Nebula Explore, our dynamic reporting service. With a Nebula Explore subscription, you'll get weekly updates based on the latest science, access to powerful tools for genome exploration, and learn more about your ancestors than with any other service.
Weekly report updates
The Nebula Research Library is a weekly updated collection of research studies curated by the scientists at Nebula Genomics. The Nebula Research Library is a great place to keep up-to-date with the latest research in human genomics and how it applies to you. For many studies in the Nebula Research Library, we calculate polygenic scores based on your genetic information and help you interpret your scores by comparing them to the scores of other Nebula Genomics users. For more information on the Nebula Research Library, please see the blog post here and explore the current content of the Nebula Research Library here.
Tools for studying the genome
Are you testing for the MTHFR gene? Do I have the rs6152 variant? How do I open my BAM file? Many of you have asked us such questions. We have found that our users are interested in different things and there isn't a single coverage that works for everyone. For this reason, we have decided to make our reporting highly dynamic and to enable user-controlled data exploration. To that end, we've developed genome research tools that will help you answer any questions about your DNA. There are three core tools. With our gene analysis tool, you can examine any gene of interest and identify relevant genetic variants and mutations. Our variant search tool allows you to search your genome for any genetic variant that has been reported in the literature. Finally, you can use our genome browser to take a direct look at your sequencing data.
Deep Ancestry Analysis
The 30-fold whole genome sequencing also allows for more comprehensive ancestral reporting than the genetic testing offered by 23andMe and AncestryDNA. This is possible because we are sequencing the entire Y chromosome (for male users) and mitochondrial DNA (for male and female users) and discovering any genetic variants present. This enables us to track paternal and maternal ancestry with much greater accuracy. In collaboration with FamilyTreeDNA, we make our ancestry reports available to give our users access to the world's largest Y chromosome and mitochondrial DNA databases and enable them to connect with relatives. Ancestry reporting will be available in the second quarter of 2020. For more information, visit the FamilyTreeDNA website Here and Here.
Full data access
We give you full access to your genome data including FASTQ, BAM and VCF files. You can always download your genome data, even if you cancel your Nebula Explore subscription.
Data protection First Genomics
In addition to providing the most cost-effective sequencing of the entire genome, we want to address the growing concerns about the privacy of genetic data that have slowed the growth of the genetic testing market directly at the consumer level. To this end, we are building a secure data management platform that combines blockchain-enabled transparency with data protection computing. This technology enables our users to benefit from affordable personal genome sequencing without compromising their privacy. You can read more about our technology here.
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